A novel electrochemical sensor with COFTZT-DVA/CNT@PB nanoflowers for hydrogen peroxide detection

Abstract

H₂O₂ is crucial for cell function, but an excess causes damage. Traditional detection methods are complex. Electrochemical methods using nanozyme-like PBNPs are simpler and more sensitive. Nanozymes require carriers to maintain stability, and COF materials are ideal carriers for nanozymes due to their good stability, abundant active sites and large specific surface area. Based on this, we successfully constructed COF_TZT-DVA/CNT@PB nanoflower-like materials for the detection of hydrogen peroxide. First, nanoflower-like COF_TZT-DVA with excellent surface area was successfully prepared using 2,4,6-tri(4-aminophenyl)-1,3,5-triazine (TZT) and 2,5-divinyl-1,4-benzenedicarboxaldehyde (DVA) at room temperature. Subsequently, PBNPs and NH₂-CNT were grown on the surface of COF_TZT-DVA, which greatly enhanced the electron transfer rate and also improved the performance of the electrochemical sensor. The nanoflower-like COF_TZT-DVA/CNT@PB has a uniform pore size and a large number of adsorption sites, which can enrich the detector and thus achieve the purpose of improving the detection sensitivity and increasing the catalytic performance of the sensor. Finally, the constructed electrochemical sensor was used for the detection of H₂O₂, and the detection limit of the sensor was calculated to be as low as 0.79 μM with a linear range of 2.38–1.05 mM.