Formaldehyde sensing by fluorescent organic sensors

Abstract

Formaldehyde is a simple molecule that can be found in different environments, having several toxic effects on both the environment and, unfortunately, humans. Therefore, the development of formaldehyde detection methods is fundamental. For this purpose, optical sensors are used, which are practical, fast and easy-to-use devices. The ideal sensor should exhibit high selectivity, sensitivity and short response time. This review summarizes the recent development in this field, highlighting the sensing properties of the systems in terms of sensitivity, selectivity and limit of detection. A comparison between the reported sensors in terms of efficiency of detection mechanisms and optical performance of different fluorophores is provided. Future perspectives of formaldehyde detection by optical probes are also provided, focusing on the current limitations that should be solved to obtain an ideal formaldehyde sensor.

Graphical abstract: Formaldehyde sensing by fluorescent organic sensors

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Article information

Article type
Review Article
Submitted
22 May 2025
Accepted
21 Jul 2025
First published
22 Jul 2025
This article is Open Access
Creative Commons BY license

Org. Biomol. Chem., 2025, Advance Article

Formaldehyde sensing by fluorescent organic sensors

R. Santonocito, A. Pappalardo, N. Tuccitto, A. Cavallaro and G. Trusso Sfrazzetto, Org. Biomol. Chem., 2025, Advance Article , DOI: 10.1039/D5OB00858A

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