Rapid access to fluorene-9-carboxamides through palladium-catalysed cross-dehydrogenative coupling

Abstract

Herein, we describe a facile synthesis of fluorene-9-carboxamides through a palladium-catalysed intramolecular cross-dehydrogenative aryl–aryl coupling reaction. The reaction features mild reaction conditions, a broad substrate scope, and simplicity of operation, constituting an interesting shortcut to access fluorene compounds.