Issue 8, 2011
From the journal:

RSC Advances

A simple method for the synthesis of hyaluronic acid coated magnetic nanoparticles for highly efficient cell labelling and in vivo imaging†

Mohammad H. El-Dakdouki,a   Kheireddine El-Boubbou,a   David C. Zhubc  and  Xuefei Huang*ac  

* Corresponding authors

a Department of Chemistry, Michigan State University, East Lansing, Michigan, USA
E-mail: xuefei@chemistry.msu.edu
Fax: +1-517-353-1793
Tel: +1-517-355-9715, Ext. 329

b Departments of Radiology and Psychology, Michigan State University, East Lansing, Michigan, USA

c Biomedical Imaging Research Centre, Michigan State University, East Lansing, Michigan, USA

Abstract

Highly stable colloidal hyaluronic acid coated magnetic nanoparticles were prepared via a ligand exchange method. These particles exhibited excellent cell labeling efficiencies and superior potential as MRI contrast agents, which are useful to target tumor cells expressing hyaluronic acid receptors such as CD44.

Graphical abstract: A simple method for the synthesis of hyaluronic acid coated magnetic nanoparticles for highly efficient cell labelling and in vivo imaging

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Article information

DOI
https://doi.org/10.1039/C1RA00737H
Article type
Communication
Submitted
15 Sep 2011
Accepted
15 Sep 2011
First published
07 Oct 2011

RSC Adv., 2011,1, 1449-1452

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A simple method for the synthesis of hyaluronic acid coated magnetic nanoparticles for highly efficient cell labelling and in vivo imaging

M. H. El-Dakdouki, K. El-Boubbou, D. C. Zhu and X. Huang, RSC Adv., 2011, 1, 1449 DOI: 10.1039/C1RA00737H

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