Issue 52, 2012

Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres

Abstract

A new, highly enantio- and diastereoselective catalytic asymmetric formal cycloaddition of aryl succinic anhydrides and aldehydes which generates paraconic acid (γ-butyrolactone) derivatives is reported.

Graphical abstract: Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres

Supplementary files

Article information

Article type
Communication
Submitted
23 Mar 2012
Accepted
01 May 2012
First published
23 May 2012

Chem. Commun., 2012,48, 6502-6504

Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres

F. Manoni, C. Cornaggia, J. Murray, S. Tallon and S. J. Connon, Chem. Commun., 2012, 48, 6502 DOI: 10.1039/C2CC32147E

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