Issue 98, 2012
From the journal:

Chemical Communications

Nucleoside phosphitylation using ionic liquid stabilised phosphorodiamidites and mechanochemistry†‡

Kerri Crossey,a   Christopher Hardacre*a  and  Marie E. Migaud*b  

* Corresponding authors

a QUILL/School of Chemistry and Chemical Engineering, Queen's University, Belfast, UK
E-mail: c.hardacre@qub.ac.uk
Fax: +44 (0)2890974687

b School of Pharmacy, Queen's University, Belfast, UK
E-mail: m.migaud@qub.ac.uk
Fax: +44 (0)28 90247794

Abstract

A range of nucleoside phosphoramidites incorporating small amino substituents have been readily synthesised using ionic liquid stabilised phosphorodiamidites coupled with mechanochemistry.

Graphical abstract: Nucleoside phosphitylation using ionic liquid stabilised phosphorodiamidites and mechanochemistry

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Article information

DOI
https://doi.org/10.1039/C2CC36367D
Article type
Communication
Submitted
31 Aug 2012
Accepted
24 Oct 2012
First published
24 Oct 2012

Chem. Commun., 2012,48, 11969-11971

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Nucleoside phosphitylation using ionic liquid stabilised phosphorodiamidites and mechanochemistry

K. Crossey, C. Hardacre and M. E. Migaud, Chem. Commun., 2012, 48, 11969 DOI: 10.1039/C2CC36367D

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