Issue 6, 2013
From the journal:

Biomaterials Science

N-Acetyl-l-cysteine capped quantum dots offer neuronal cell protection by inhibiting beta (1–40) amyloid fibrillation†

Olivia T. W. Ng,‡a   Yi Wong,‡b   Ho-Man Chan,b   Jing Cheng,b   Xiao Qi,b   Wing-Hong Chan,b   Ken K. L. Yung*a  and  Hung-Wing Li*b  

* Corresponding authors

a Department of Biology, Hong Kong Baptist University, Kowloon Tong, Hong Kong, P. R. China
E-mail: kklyung@hkbu.edu.hk
Fax: +852-3411-5995
Tel: +852-3411-7060

b Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, P. R. China
E-mail: hwli@hkbu.edu.hk
Fax: +852-3411-7348
Tel: +852-3411-7065

Abstract

This is the first work that revealed the neuro-protective effect of functionalized quantum dots against the cytotoxicity induced by beta-amyloid peptides. This study gives insight into the future treatment of Alzheimer's disease. It opens many avenues for the development of the next generation nanotechnology for biomedical and therapeutic applications.

Graphical abstract: N-Acetyl-l-cysteine capped quantum dots offer neuronal cell protection by inhibiting beta (1–40) amyloid fibrillation

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Article information

DOI
https://doi.org/10.1039/C3BM60029G
Article type
Communication
Submitted
31 Jan 2013
Accepted
28 Mar 2013
First published
17 Apr 2013

Biomater. Sci., 2013,1, 577-580

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N-Acetyl-L-cysteine capped quantum dots offer neuronal cell protection by inhibiting beta (1–40) amyloid fibrillation

O. T. W. Ng, Y. Wong, H. Chan, J. Cheng, X. Qi, W. Chan, K. K. L. Yung and H. Li, Biomater. Sci., 2013, 1, 577 DOI: 10.1039/C3BM60029G

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