Issue 27, 2013
From the journal:

Chemical Communications

Tuneable nanochannel formation for sample-in/answer-out devices†‡

Aliaa I. Shallan,ab   Adam J. Gaudry,a   Rosanne M. Guijtb  and  Michael C. Breadmore*a  

* Corresponding authors

a Australian Centre for Research on Separation Science, School of Chemistry, University of Tasmania, Private Bag 75, Hobart, Australia
E-mail: mcb@utas.edu.au
Fax: +61-3-6226-2858
Tel: +61-3-6226-2154

b Australian Centre for Research on Separation Science, School of Pharmacy, University of Tasmania, Private Bag 26, Hobart, Australia

Abstract

Control of the dielectric breakdown of PDMS was achieved by limiting the current during the breakdown process. This enabled tuning of the nanochannel pore size and hence their permeability for molecules of different molecular weights. This method enabled the analysis of the drug quinine from whole blood in 3 min using a simple, disposable microfluidic device.

Graphical abstract: Tuneable nanochannel formation for sample-in/answer-out devices

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Article information

DOI
https://doi.org/10.1039/C3CC38330J
Article type
Communication
Submitted
19 Nov 2012
Accepted
23 Jan 2013
First published
30 Jan 2013

Chem. Commun., 2013,49, 2816-2818

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Tuneable nanochannel formation for sample-in/answer-out devices

A. I. Shallan, A. J. Gaudry, R. M. Guijt and M. C. Breadmore, Chem. Commun., 2013, 49, 2816 DOI: 10.1039/C3CC38330J

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