Issue 1, 2014
From the journal:

Chemical Communications

Fluorescence modification of the AAAA (4A) loop: toward a probe of the structural dynamics of the i-motif of the retinoblastoma gene†

Jung Woo Park,a   Young Jun Seo*b  and  Byeang Hyean Kim*a  

* Corresponding authors

a Department of Chemistry, BK School of Molecular Science, Pohang University of Science and Technology, Pohang 790-784, South Korea
E-mail: bhkim@postech.ac.kr
Fax: +82-54-279-3399
Tel: +82-54-279-2115

b Department of Chemistry, Chonbuk National University, Jeonju 561-756, South Korea
E-mail: yseo@jbnu.ac.kr
Fax: +82-63-270-3408
Tel: +82-63-270-3417

Abstract

Systematic modification of the 4A loop region of the Rb gene with PyA fluorophore units allows discrimination of the fluorescence signals corresponding to structural dynamics from single-stranded to i-motif structures.

Graphical abstract: Fluorescence modification of the AAAA (4A) loop: toward a probe of the structural dynamics of the i-motif of the retinoblastoma gene

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C3CC46619A
Article type
Communication
Submitted
29 Aug 2013
Accepted
21 Oct 2013
First published
22 Oct 2013

Chem. Commun., 2014,50, 52-54

Permissions

Request permissions

Fluorescence modification of the AAAA (4A) loop: toward a probe of the structural dynamics of the i-motif of the retinoblastoma gene

J. W. Park, Y. J. Seo and B. H. Kim, Chem. Commun., 2014, 50, 52 DOI: 10.1039/C3CC46619A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements