Issue 10, 2014

Synthesis of benzofurans via ruthenium-catalyzed redox-neutral C–H functionalization and reaction with alkynes under mild conditions

Abstract

Using an oxidizing directing group, a mild RuII-catalyzed direct coupling of N-phenoxypivalamide with internal alkynes was developed, generating the benzofurans in moderate to high yields.

Graphical abstract: Synthesis of benzofurans via ruthenium-catalyzed redox-neutral C–H functionalization and reaction with alkynes under mild conditions

Supplementary files

Article information

Article type
Research Article
Submitted
14 Jul 2014
Accepted
15 Sep 2014
First published
16 Sep 2014

Org. Chem. Front., 2014,1, 1161-1165

Synthesis of benzofurans via ruthenium-catalyzed redox-neutral C–H functionalization and reaction with alkynes under mild conditions

Z. Zhou, G. Liu, Y. Shen and X. Lu, Org. Chem. Front., 2014, 1, 1161 DOI: 10.1039/C4QO00196F

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