Annulation based on 8-aminoquinoline assisted C–H activation: an emerging tool in N-heterocycle construction

Abstract

The synthesis of heterocyclic products via C–H activation has won impressive advances as a newly emerging synthetic strategy. Herein, the recent research advances in heterocycle synthesis employing 8-aminoquinoline directed C–H activation, either in the form of direct intramolecular C–H elaboration or domino reactions involving the C–H activation and other transformation-based annulation reactions are highlighted.