Issue 11, 2021
From the journal:

Chemical Society Reviews

Radical trifluoromethylation

Haiwen Xiao,†a   Zhenzhen Zhang,†b   Yewen Fang, ORCID logo *a   Lin Zhu*b  and  Chaozhong Li ORCID logo *ab  

* Corresponding authors

a School of Materials and Chemical Engineering, Ningbo University of Technology, 201 Fenghua Road, Ningbo 315211, China
E-mail: fang@nbut.edu.cn

b Key Laboratory of Organofluorine Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China
E-mail: clig@mail.sioc.ac.cn, zhulin@sioc.ac.cn

Abstract

The trifluoromethyl group plays an increasingly important role in pharmaceuticals, agrochemicals and materials. This tutorial describes recent advances in trifluoromethylation of carbon-centered radical intermediates.

Graphical abstract: Radical trifluoromethylation

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Article information

DOI
https://doi.org/10.1039/D1CS00200G
Article type
Tutorial Review
Submitted
23 Feb 2021
First published
23 Apr 2021

Chem. Soc. Rev., 2021,50, 6308-6319

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Radical trifluoromethylation

H. Xiao, Z. Zhang, Y. Fang, L. Zhu and C. Li, Chem. Soc. Rev., 2021, 50, 6308 DOI: 10.1039/D1CS00200G

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