Ru(0)-Catalysed synthesis of borylated polyene building blocks by cross-dimerisation toward cross-coupling

Abstract

Conjugated and non-conjugated polyenes are important substructures and often found in biologically active compounds and natural products. These preparations often need multiple steps or iterative reactions and as a result they have poor step economies. In this feature article, we show a new methodology to prepare these substractures by combinations of cross-dimerisation giving borylated polyenes and subsequent cross-coupling reactions. This divergent reaction allows for opportunity to access many bioactive compounds and natural products as well as some electronic materials.