Direct and chemoselective transformation of cysteine to dehydroalanine on peptides

Abstract

A direct method for the preparation of peptides containing a dehydroalanine residue was developed through the chemoselective transformation of a cysteine residue in peptides, under the influence of cesium carbonate.

Supplementary files

Article information

Article type
Communication
Submitted
10 Jan 2025
Accepted
25 Feb 2025
First published
26 Feb 2025

Chem. Commun., 2025, Accepted Manuscript

Direct and chemoselective transformation of cysteine to dehydroalanine on peptides

T. Mori, K. Sakata and S. Shirakawa, Chem. Commun., 2025, Accepted Manuscript , DOI: 10.1039/D5CC00156K

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