Visible-light-induced C–H alkylation of pyridine derivatives via 1,2-hydrogen atom transfer

Abstract

A visible-light-induced radical–radical cross-coupling protocol between hydroxamic acid derivatives and pyridine derivatives for the synthesis of pyridin-2-ylmethanamine derivatives via 1,2-hydrogen atom transfer has been reported. This protocol features metal-free and mild reaction conditions, a broad range of substrates, remarkable functional group tolerance and potential application.