Design, synthesis, and biological evaluation of novel N-(1H-indazol-6-yl)benzenesulfonamide derivatives as potent PLK4 inhibitors

Abstract

Pengkun Sun1, Cunzheng Fan1, Nian Liu1, Minghui Tong, Xuan Shi, Han Wang, Shuyi Mu, Ningyuan Hu, Yixiang Sun, Haoyu Zhang, Zixuan Gao, Dongmei Zhao* , Maosheng Cheng

Supplementary files

Article information

Article type
Research Article
Submitted
21 Mar 2025
Accepted
13 May 2025
First published
13 May 2025

RSC Med. Chem., 2025, Accepted Manuscript

Design, synthesis, and biological evaluation of novel N-(1H-indazol-6-yl)benzenesulfonamide derivatives as potent PLK4 inhibitors

P. Sun, C. Fan, N. liu, M. Tong, X. Shi, H. Wang, S. Mu, N. Hu, Y. sun, H. Zhang, Z. Gao, D. Zhao and M. Cheng, RSC Med. Chem., 2025, Accepted Manuscript , DOI: 10.1039/D5MD00251F

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