Themed collection Biomaterials for Imaging and Sensing

23 items
Editorial

Introduction to Biomaterials for Imaging and Sensing

Guest editors Jesse Jokerst and Kanyi Pu introduce the Biomaterials Science themed collection on Biomaterials for Imaging and Sensing.

Graphical abstract: Introduction to Biomaterials for Imaging and Sensing
From the themed collection: Biomaterials for Imaging and Sensing
Minireview

Synergistic agents for tumor-specific therapy mediated by focused ultrasound treatment

In this minireview, synergistic agents for focused ultrasound tumor treatment are reviewed in four therapy mechanisms: sonodynamic plus chemotherapy, microbubble-aided therapy, localized drug delivery, and photoacoustic image-guided therapy.

Graphical abstract: Synergistic agents for tumor-specific therapy mediated by focused ultrasound treatment
From the themed collection: Biomaterials for Imaging and Sensing
Minireview

Recent advances in stimuli-responsive in situ self-assembly of small molecule probes for in vivo imaging of enzymatic activity

Stimuli-responsive in situ self-assembly of small molecule probes into nanostructures has been promising for the construction of molecular probes for in vivo imaging.

Graphical abstract: Recent advances in stimuli-responsive in situ self-assembly of small molecule probes for in vivo imaging of enzymatic activity
From the themed collection: Biomaterials for Imaging and Sensing
Review Article

Gold nanoparticles to enhance ophthalmic imaging

Gold nanoparticles are promising OCT and PAI contrast agents for ophthalmic imaging because of their high light scattering/absorption from SPR.

Graphical abstract: Gold nanoparticles to enhance ophthalmic imaging
From the themed collection: Biomaterials for Imaging and Sensing
Review Article

More than skin deep: using polymers to facilitate topical delivery of nitric oxide

Polymers can facilitate delivery of nitric oxide, improving stability and control of release for effective treatment of common skin disorders.

Graphical abstract: More than skin deep: using polymers to facilitate topical delivery of nitric oxide
From the themed collection: Biomaterials for Imaging and Sensing
Review Article

Peptide-based supramolecular hydrogels for bioimaging applications

Peptide-based supramolecular hydrogels have unique merits in bioimaging applications.

Graphical abstract: Peptide-based supramolecular hydrogels for bioimaging applications
From the themed collection: Biomaterials for Imaging and Sensing
Review Article

Medical imaging of tissue engineering and regenerative medicine constructs

This review discusses key outcome measures for TERM constructs and various imaging techniques that can be used to assess them.

Graphical abstract: Medical imaging of tissue engineering and regenerative medicine constructs
From the themed collection: Biomaterials for Imaging and Sensing
Review Article

Hybridizing clinical translatability with enzyme-free DNA signal amplifiers: recent advances in nucleic acid detection and imaging

Strand amplifying HCR and CHA are adaptable with signalers for novel and clinically translatable nucleic acid sensors and imaging agents.

Graphical abstract: Hybridizing clinical translatability with enzyme-free DNA signal amplifiers: recent advances in nucleic acid detection and imaging
From the themed collection: Biomaterials for Imaging and Sensing
Review Article

Recent advances in semiconducting polymer dots as optical probes for biosensing

This review mainly summarized the recent results that used bright polymer dots (Pdots) for the detection of different analytes such as reactive oxygen species (ROS), metal ions, pH values, and a variety of biomolecules.

Graphical abstract: Recent advances in semiconducting polymer dots as optical probes for biosensing
From the themed collection: Biomaterials for Imaging and Sensing
Review Article

The development of phosphorescent probes for in vitro and in vivo bioimaging

This review mainly introduces the phosphorescent probes applied in vitro and in vivo bioimaging.

Graphical abstract: The development of phosphorescent probes for in vitro and in vivo bioimaging
From the themed collection: Biomaterials for Imaging and Sensing
Review Article

Recent advances in improving tumor-targeted delivery of imaging nanoprobes

This review discusses various recent strategies based on different targeting ligands to improve the tumor-specific targeting of nanoprobes toward precision imaging diagnosis.

Graphical abstract: Recent advances in improving tumor-targeted delivery of imaging nanoprobes
From the themed collection: Biomaterials for Imaging and Sensing
Communication

A peptide-based aggregation-induced emission bioprobe for selective detection and photodynamic killing of Gram-negative bacteria

A bioprobe with aggregation-induced emission characteristics is developed, which can visualize and photodynamically ablate Gram-negative bacteria in a selective manner.

Graphical abstract: A peptide-based aggregation-induced emission bioprobe for selective detection and photodynamic killing of Gram-negative bacteria
From the themed collection: Biomaterials for Imaging and Sensing
Paper

Nanocarriers targeting adipose macrophages increase glucocorticoid anti-inflammatory potency to ameliorate metabolic dysfunction

Obesity is associated with systemic inflammation due to macrophage accumulation in adipose tissue (AT).

Graphical abstract: Nanocarriers targeting adipose macrophages increase glucocorticoid anti-inflammatory potency to ameliorate metabolic dysfunction
From the themed collection: Biomaterials for Imaging and Sensing
Paper

Tb-Doped core–shell–shell nanophosphors for enhanced X-ray induced luminescence and sensitization of radiodynamic therapy

Tb doped core/shell/shell nanophosphor exhibits robust X-ray luminescence and potential in radiodynamic therapy.

Graphical abstract: Tb-Doped core–shell–shell nanophosphors for enhanced X-ray induced luminescence and sensitization of radiodynamic therapy
From the themed collection: Biomaterials for Imaging and Sensing
Paper

A colorful approach towards developing new nano-based imaging contrast agents for improved cancer detection

Coloring dyes reveal potential as optical imaging contrast agents for cancer detection. Tattoo and Design created by artist Adam Sky.

Graphical abstract: A colorful approach towards developing new nano-based imaging contrast agents for improved cancer detection
From the themed collection: Biomaterials for Imaging and Sensing
Paper

Quenched cetuximab conjugate for fast fluorescence imaging of EGFR-positive lung cancers

We developed ATTO655 dye-conjugated cetuximab for fast and real-time fluorescence imaging of EGFR-positive lung cancers.

Graphical abstract: Quenched cetuximab conjugate for fast fluorescence imaging of EGFR-positive lung cancers
From the themed collection: Biomaterials for Imaging and Sensing
Paper

A highly selective iron oxide-based imaging nanoparticle for long-term monitoring of drug-induced tumor cell apoptosis

PSA was conjugated onto IONP by first covalently linking Neu onto a 10 nm IONP core and then attaching PSA to neu via biotin–avidin interaction. When applied in vivo, IONP-Neu-PSA-Cy5.5 produced persistent near-IR signal specifically for monitoring tumor apoptosis.

Graphical abstract: A highly selective iron oxide-based imaging nanoparticle for long-term monitoring of drug-induced tumor cell apoptosis
From the themed collection: Biomaterials for Imaging and Sensing
Paper

Theranostic supramolecular polymers formed by the self-assembly of a metal-chelating prodrug

The direct linkage of two camptothecin moieties to a metal chelator creates a self-assembling prodrug capable of associating in aqueous solution into theranostic supramolecular polymers.

Graphical abstract: Theranostic supramolecular polymers formed by the self-assembly of a metal-chelating prodrug
From the themed collection: Biomaterials for Imaging and Sensing
Paper

Novel anilino quinazoline-based EGFR tyrosine kinase inhibitors for treatment of non-small cell lung cancer

The two novel anilino quinazoline-based EGFR-TKIs have promising anti-tumor activity and limited hepatotoxicity, representing excellent candidates for combating the NSCLC.

Graphical abstract: Novel anilino quinazoline-based EGFR tyrosine kinase inhibitors for treatment of non-small cell lung cancer
From the themed collection: Biomaterials for Imaging and Sensing
Paper

Facile formulation of a long-wavelength cyanine for optical imaging in the second near-infrared window

A dozen commercial NIR-II dyes are screened for simple formulation and one is applied for in vivo optical imaging in mice.

Graphical abstract: Facile formulation of a long-wavelength cyanine for optical imaging in the second near-infrared window
From the themed collection: Biomaterials for Imaging and Sensing
Paper

Cocaine analogue conjugated magnetic nanoparticles for labeling and imaging dopaminergic neurons

An iron oxide nanoparticle conjugated with a cocaine analogue exhibits small size and long-term stability with the ability to target dopamine transporter-expressing neurons and provides excellent contrast enhancement under MRI, demonstrating great potential for neuroimaging.

Graphical abstract: Cocaine analogue conjugated magnetic nanoparticles for labeling and imaging dopaminergic neurons
From the themed collection: Biomaterials for Imaging and Sensing
Paper

Peptide assembly assisted triplet–triplet annihilation photon upconversion in non-deoxygenated water

Peptide-tuned TTA-UC luminescence is reported by the formation of UC chromophore-assembled tetrahedral nanorods. Intense UC emission from the upconversion donor to acceptor in nanorods can be observed in non-deoxygenated water.

Graphical abstract: Peptide assembly assisted triplet–triplet annihilation photon upconversion in non-deoxygenated water
From the themed collection: Biomaterials for Imaging and Sensing
Paper

In situ self-assembly of conjugated polyelectrolytes for cancer targeted imaging and photodynamic therapy

Both the specific aggregation of PFT-SH in cancer cells and its ROS producing ability led to its use in the targeted killing of cancer cells through efficient photodynamic therapy.

Graphical abstract: In situ self-assembly of conjugated polyelectrolytes for cancer targeted imaging and photodynamic therapy
From the themed collection: Biomaterials for Imaging and Sensing
23 items

About this collection

A collection of original research and reviews focussing on Biomaterials for Imaging and Sensing. The goal of this collection is to highlight the most exciting advances in responsive materials, as applied to real-time analysis of analytes relevant to life sciences including proteins, electrolytes and cells. Both in vivo and in vitro measurements were welcome. Here, we define biomaterials broadly including any number of soft or hard materials including plasmonic materials, polymeric systems, self-condensing approaches, biomimicry etc.
 
Guest Edited by Jesse Jokerst (UC San Diego, USA) and Kanyi Pu (Nanyang Technological University, Singapore).

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