Themed collection Novel stable isotopes in health sciences
The potential for a carbon stable isotope biomarker of dietary sugar intake
Added sugar is sweetener added to foods during processing or preparation that offers no health benefits to the consumer.
J. Anal. At. Spectrom., 2014,29, 795-816
https://doi.org/10.1039/C3JA50339A
The emerging role of carbon isotope ratio determination in health research and medical diagnostics
Variations in the isotopic signature of carbon in biological samples (e.g. breath, blood and tissues) can be used to monitor shifts in whole body metabolism.
J. Anal. At. Spectrom., 2014,29, 594-598
https://doi.org/10.1039/C3JA50327E
The expired breath carbon delta value is a marker for the onset of sepsis in a swine model
Approximately 750 000 people develop sepsis each year with more than 215 000 deaths.
J. Anal. At. Spectrom., 2014,29, 606-613
https://doi.org/10.1039/C3JA50340B
Changes in breath carbon isotope composition as a potential biomarker of inflammatory acute phase response in mechanically ventilated pediatric patients
Sepsis is a leading cause of mortality in intensive care units.
J. Anal. At. Spectrom., 2014,29, 599-605
https://doi.org/10.1039/C3JA50331C
The influence of menstrual blood loss and age on the isotopic composition of Cu, Fe and Zn in human whole blood
To assess the effect of menstruation on the isotopic composition of whole blood Cu, Fe and Zn, samples from two groups of non-menstruating women were analyzed using multi-collector ICP-MS and the results were compared to the values for a male and a female reference population.
J. Anal. At. Spectrom., 2014,29, 478-482
https://doi.org/10.1039/C3JA50269D
An inter-laboratory comparison of high precision stable isotope ratio measurements for nanoparticle tracing in biological samples
The first independent confirmation that high precision stable isotope labeling is robust when used to trace nanoparticles in biological systems.
J. Anal. At. Spectrom., 2014,29, 471-477
https://doi.org/10.1039/C3JA50322D
Evidence for a possible dietary effect on the isotopic composition of Zn in blood via isotopic analysis of food products by multi-collector ICP-mass spectrometry
The hypothesis of a possible dietary effect on the isotopic composition of Zn in blood from lacto-ovo vegetarians and omnivores was investigated through isotopic analysis of Zn in food products by MC-ICP-MS.
Metallomics, 2014,6, 139-146
https://doi.org/10.1039/C3MT00244F
About this collection
This collection of papers highlights the growing field of the use of natural stable isotope fractionation in health sciences, both for understanding homeostasis in normal and pathological conditions and as potential new biomarkers. Guest Edited by Ariel Anbar, Vincent Balter and Frank Vanhaecke. New articles will be added to this collection as they are published.