Review Article
Advancements in enzyme immobilization on magnetic nanomaterials: toward sustainable industrial applications
Enzymes are widely used in biofuels, food, and pharmaceuticals.
Review Article
Advances in chromone-based copper(II) Schiff base complexes: synthesis, characterization, and versatile applications in pharmacology and biomimetic catalysis
Chromones are well known as fundamental structural elements found in numerous natural compounds and medicinal substances.
Paper
Combining de novo molecular design with semiempirical protein–ligand binding free energy calculation
Semi-empirical quantum chemistry methods estimate the binding free energies of de novo generated ligand–protein complexes.
Paper
Sugar mimics and their probable binding sites: design and synthesis of thiazole linked coumarin-piperazine hybrids as galectin-1 inhibitors
Synthesis of Gal-1 inhibitors with binding site analysis using 1.2 μs MD replicas and machine learning.
Paper
Reaction contest: hydrolysis versus intramolecular cyclisation reaction in alkyl squaramate esters
The hydrolytic behavior and stability of squaramate esters have been investigated, shedding light on the competition between hydrolysis and intramolecular cyclization reactions, which is crucial for advancing bioconjugate chemistry applications.
Paper
Synthesis, anticancer evaluation of novel hybrid pyrazole-based chalcones, molecular docking, DNA fragmentation, and gene expression: in vitro studies
A new series of pyrazole-based chalcones were synthesized and tested against MCF7, PC3, PACA2 and BJ1 as in vitro study. Gene expression, DNA damage, DNA fragmentation and molecular docking for were discussed.
Paper
Discovery of new triterpene glycosides from Dendrobium officinale with their α-glucosidase and α-amylase inhibitory activity
Seven new oleanane saponins were discovered from Dendrobium officinale. These saponins containing 29-noroleana-12,20(30)-dien-28-oic acid framework, caffeoyl, and coumaroyl moieties potentially inhibited α-glucosidase and α-amylase activities.
About this collection
Welcome to RSC Advances Biological & Medicinal Chemistry year in review for 2024!
The articles in this collection have been selected as they have gained great attention within their first year of being published.
We hope you enjoy reading these articles and congratulations to all the authors whose articles are featured!