Themed collection Journal of Materials Chemistry B Emerging Investigators 2025

15 items
Accepted Manuscript - Review Article

Versatility of LNPs across different administration routes for targeted RNA delivery

Accepted Manuscript - Review Article

Decoding Tissue Complexity: Multiscale Mapping of Chemistry-structure-function Relationships through Advanced Visualization Technologies

Review Article

Photo-responsive antibacterial metal organic frameworks

Metal organic frameworks with diverse photo-responsive antibacterial mechanisms for biomedical applications are summarized.

Graphical abstract: Photo-responsive antibacterial metal organic frameworks
Communication

Carbon dots with wide-spectrum absorption for enhanced anti-aging of poly(vinyl chloride) films

Eco-friendly carbon dots synthesized from Garcinia mangostana rind via solvothermal methods enhance PVC film photostability and mechanical properties, offering promising durability for sunlight-exposed applications such as food packaging.

Graphical abstract: Carbon dots with wide-spectrum absorption for enhanced anti-aging of poly(vinyl chloride) films
Communication

A self-assembled copper-artemisinin nanoprodrug as an efficient reactive oxygen species amplified cascade system for cancer treatment

Self-assembled nanoprodrug was constructed via coordinative interactions between artesunate-histidine conjugate and copper ions, serving as efficient Fenton-like reagent for robust ROS generation toward tumor therapy both in vitro and in vivo.

Graphical abstract: A self-assembled copper-artemisinin nanoprodrug as an efficient reactive oxygen species amplified cascade system for cancer treatment
Accepted Manuscript - Paper

Zwitterionic-based cyclic brush polymer nanomicelles with improved lubrication and antioxidation properties

Paper

Dual model biosensor integrated with peroxidase-like activity and self-assembly for uric acid detection

A hollow Cu2O@Au nanocube-based dual-model biosensor was developed for uric acid detection, combining colorimetry and laser desorption/ionization mass spectrometry.

Graphical abstract: Dual model biosensor integrated with peroxidase-like activity and self-assembly for uric acid detection
Paper

Carbon-based nanomaterials with higher specific surface area: more expensive but more effective antimicrobials

Titanium dental implants are prone to infections by pathogenic bacteria, leading to the formation of biofilm and development of peri-implantitis.

Graphical abstract: Carbon-based nanomaterials with higher specific surface area: more expensive but more effective antimicrobials
Paper

A bioactive Cu-grafted gel coating with micro–nano structures for simultaneous enhancement of bone regeneration and infection resistance

To prevent PJI, PVA–TP–CA/Cu@TC4 was obtained by constructing a micro–nano structure on TC4 and loading a PVA gel coating, which exhibited enhanced biofunctional properties, including antibacterial, angiogenesis, and osteogenic activities.

Graphical abstract: A bioactive Cu-grafted gel coating with micro–nano structures for simultaneous enhancement of bone regeneration and infection resistance
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Towards injured joint rehabilitation: structural color hydrogels for accelerated wound healing and rehabilitation exercise monitoring

A structural color hydrogel composed of a hybrid double-network is developed for accelerated wound healing and rehabilitation exercise monitoring.

Graphical abstract: Towards injured joint rehabilitation: structural color hydrogels for accelerated wound healing and rehabilitation exercise monitoring
From the themed collection: Journal of Materials Chemistry B HOT Papers
Paper

Guanidyl-rich α-helical polypeptide enables efficient cytosolic pro-protein delivery and CRISPR-Cas9 genome editing

An LPP binds to A-protein via electrostatic attraction and hydrogen bonding to form stable NCs. Upon endocytosis, the LPP induces rapid endolysosomal escape, and the native protein is restored by cleaving boronate ester and imine caging groups.

Graphical abstract: Guanidyl-rich α-helical polypeptide enables efficient cytosolic pro-protein delivery and CRISPR-Cas9 genome editing
Paper

Direct covalent attachment of fluorescent molecules on plasma polymerized nanoparticles: a simplified approach for biomedical applications

This paper provides first-time evidence of covalent attachment of fluorescent molecules to plasma polymerised nanoparticles for diagnostic and therapeutic applications.

Graphical abstract: Direct covalent attachment of fluorescent molecules on plasma polymerized nanoparticles: a simplified approach for biomedical applications
Paper

Regulation of macrophage uptake through the bio-nano interaction using surface functionalized mesoporous silica nanoparticles with large radial pores

This study investigates the impact of surface modifications on the protein corona formation around mesoporous silica nanoparticles, revealing how these modifications influence macrophage uptake.

Graphical abstract: Regulation of macrophage uptake through the bio-nano interaction using surface functionalized mesoporous silica nanoparticles with large radial pores
Paper

Nanocrystalline alloy-mediated delivery of mosaic epitope peptides for universal influenza vaccine

Mosaic influenza antimicrobial peptide-like epitopes (Ampitopes) co-crystalize with poly(I:C), a TLR3 agonist, into nanocrystalline vaccine, which boosts immunogenicity via multivalent toll like receptor 3 (TLR3) binding and immune activation.

Graphical abstract: Nanocrystalline alloy-mediated delivery of mosaic epitope peptides for universal influenza vaccine
Paper

Near-infrared activated liposomes for neuroprotection in glaucoma

Gold nanorods-encapsulated liposomes enabled the on-demand release of melatonin in mouse glaucoma models.

Graphical abstract: Near-infrared activated liposomes for neuroprotection in glaucoma
15 items

About this collection

Journal of Materials Chemistry B is pleased to present this themed collection highlighting the rising stars of materials chemistry research in 2025. This special collection showcases the very best work from materials chemists in the early stages of their independent career.

Each contributor was recommended by experts in their fields as carrying out work with the potential to influence future directions in materials chemistry with applications in biology and medicine. Congratulations to all the outstanding researchers featured!

See also:

Journal of Materials Chemistry A Emerging Investigators 2025

Journal of Materials Chemistry C Emerging Investigators 2025

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