Themed collection Journal of Materials Chemistry B Emerging Investigators 2025

6 items
Communication

A self-assembled copper-artemisinin nanoprodrug as an efficient reactive oxygen species amplified cascade system for cancer treatment

Self-assembled nanoprodrug was constructed via coordinative interactions between artesunate-histidine conjugate and copper ions, serving as efficient Fenton-like reagent for robust ROS generation toward tumor therapy both in vitro and in vivo.

Graphical abstract: A self-assembled copper-artemisinin nanoprodrug as an efficient reactive oxygen species amplified cascade system for cancer treatment
Paper

Guanidyl-rich α-helical polypeptide enables efficient cytosolic pro-protein delivery and CRISPR-Cas9 genome editing

An LPP binds to A-protein via electrostatic attraction and hydrogen bonding to form stable NCs. Upon endocytosis, the LPP induces rapid endolysosomal escape, and the native protein is restored by cleaving boronate ester and imine caging groups.

Graphical abstract: Guanidyl-rich α-helical polypeptide enables efficient cytosolic pro-protein delivery and CRISPR-Cas9 genome editing
Paper

Direct covalent attachment of fluorescent molecules on plasma polymerized nanoparticles: a simplified approach for biomedical applications

This paper provides first-time evidence of covalent attachment of fluorescent molecules to plasma polymerised nanoparticles for diagnostic and therapeutic applications.

Graphical abstract: Direct covalent attachment of fluorescent molecules on plasma polymerized nanoparticles: a simplified approach for biomedical applications
Paper

Regulation of macrophage uptake through the bio-nano interaction using surface functionalized mesoporous silica nanoparticles with large radial pores

This study investigates the impact of surface modifications on the protein corona formation around mesoporous silica nanoparticles, revealing how these modifications influence macrophage uptake.

Graphical abstract: Regulation of macrophage uptake through the bio-nano interaction using surface functionalized mesoporous silica nanoparticles with large radial pores
Paper

Nanocrystalline alloy-mediated delivery of mosaic epitope peptides for universal influenza vaccine

Mosaic influenza antimicrobial peptide-like epitopes (Ampitopes) co-crystalize with poly(I:C), a TLR3 agonist, into nanocrystalline vaccine, which boosts immunogenicity via multivalent toll like receptor 3 (TLR3) binding and immune activation.

Graphical abstract: Nanocrystalline alloy-mediated delivery of mosaic epitope peptides for universal influenza vaccine
Paper

Near-infrared activated liposomes for neuroprotection in glaucoma

Gold nanorods-encapsulated liposomes enabled the on-demand release of melatonin in mouse glaucoma models.

Graphical abstract: Near-infrared activated liposomes for neuroprotection in glaucoma
6 items

About this collection

Journal of Materials Chemistry B is pleased to present this themed collection highlighting the rising stars of materials chemistry research in 2025. This special collection showcases the very best work from materials chemists in the early stages of their independent career.

Each contributor was recommended by experts in their fields as carrying out work with the potential to influence future directions in materials chemistry with applications in biology and medicine. Congratulations to all the outstanding researchers featured!

See also:

Journal of Materials Chemistry A Emerging Investigators 2025

Journal of Materials Chemistry C Emerging Investigators 2025

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