Issue 9, 2017

Lu's [3 + 2] cycloaddition of allenes with electrophiles: discovery, development and synthetic application

Abstract

Lu's [3 + 2] cycloaddition reaction has experienced explosive development due to its versatile and powerful ability to access highly functionalized carbo- and heterocycles. After the first example reported by Prof. Xiyan Lu's group, many research groups expanded its substrate scope, and developed its asymmetric variants, and demonstrated its synthetic applications as well. This review briefly introduces the history of Lu's [3 + 2] cycloaddition reaction and highlights the important developments and synthetic applications with respect to Lu's [3 + 2] cycloaddition reaction.

Graphical abstract: Lu's [3 + 2] cycloaddition of allenes with electrophiles: discovery, development and synthetic application

Article information

Article type
Review Article
Submitted
15 מאי 2017
Accepted
19 יונ 2017
First published
20 יונ 2017

Org. Chem. Front., 2017,4, 1876-1890

Lu's [3 + 2] cycloaddition of allenes with electrophiles: discovery, development and synthetic application

Y. Wei and M. Shi, Org. Chem. Front., 2017, 4, 1876 DOI: 10.1039/C7QO00285H

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