Issue 75, 2022

Phosphine-mediated three-component bioconjugation of amino- and azidosaccharides in ionic liquids

Abstract

Bioconjugation of carbohydrates has been a challenging task because of their chemical, functional, and structural diversities, and no single chemical modification tool can be universally applicable to all the target substrates in different environments. In this report, we have developed a bioconjugation strategy for labeling of carbohydrate derivatives through a phosphine-mediated three-component coupling reaction in an ionic liquid medium.

Graphical abstract: Phosphine-mediated three-component bioconjugation of amino- and azidosaccharides in ionic liquids

Supplementary files

Article information

Article type
Communication
Submitted
18 יול 2022
Accepted
18 אוג 2022
First published
19 אוג 2022

Chem. Commun., 2022,58, 10568-10571

Phosphine-mediated three-component bioconjugation of amino- and azidosaccharides in ionic liquids

Y. D. Hall, C. P. Uzoewulu, Z. M. Nizam, S. Ishizawa, H. M. El-Shaffey and J. Ohata, Chem. Commun., 2022, 58, 10568 DOI: 10.1039/D2CC04013A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements