Gen Liu, Zixuan Chen, Bao-Kang Jin and Li-Ping Jiang
Analyst, 2021,146, 1835-1838
DOI:
10.1039/D0AN02408B,
Communication
Here, we proposed a ratiometric electrochemiluminescent (ECL) strategy in spatially multiplied ECL systems. By the specific recognition of hyaluronic acid with proteoglycan CD44 and epidermal growth factor with epidermal growth factor receptor on the cell surface, the cells were labelled with potential-resolved ECL probes, namely Ru(bpy)32+ and g-C3N4, respectively. The as-proposed cytosensor provides a multichannel ECL protocol to improve the throughput, which may push the application of ECL for the cellular immunoanalysis.