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A robust and sustainable C(sp2)–C(sp3) cross-electrophile coupling was developed via nickel/copper synergistic catalysis under micellar conditions. This protocol provided a general method to access alkylated arenes with good to excellent yields on a very large scale.

Graphical abstract: Micelle enabled C(sp2)–C(sp3) cross-electrophile coupling in water via synergistic nickel and copper catalysis

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