Issue 11, 2024

Porphyrin-based covalent organic frameworks from design, synthesis to biological applications

Abstract

Covalent organic frameworks (COFs) constitute a class of highly functional porous materials composed of lightweight elements interconnected by covalent bonds, characterized by structural order, high crystallinity, and large specific surface area. The integration of naturally occurring porphyrin molecules, renowned for their inherent rigidity and conjugate planarity, as building blocks in COFs has garnered significant attention. This strategic incorporation addresses the limitations associated with free-standing porphyrins, resulting in the creation of well-organized porous crystal structures with molecular-level directional arrangements. The unique optical, electrical, and biochemical properties inherent to porphyrin molecules endow these COFs with diversified applications, particularly in the realm of biology. This review comprehensively explores the synthesis and modulation strategies employed in the development of porphyrin-based COFs and delves into their multifaceted applications in biological contexts. A chronological depiction of the evolution from design to application is presented, accompanied by an analysis of the existing challenges. Furthermore, this review offers directional guidance for the structural design of porphyrin-based COFs and underscores their promising prospects in the field of biology.

Graphical abstract: Porphyrin-based covalent organic frameworks from design, synthesis to biological applications

Article information

Article type
Review Article
Submitted
08 feb. 2024
Accepted
15 apr. 2024
First published
20 apr. 2024
This article is Open Access
Creative Commons BY-NC license

Biomater. Sci., 2024,12, 2766-2785

Porphyrin-based covalent organic frameworks from design, synthesis to biological applications

X. Li, J. Li, J. Chen, L. Rao, L. Zheng, F. Yu, Y. Tang, J. Zheng and J. Ma, Biomater. Sci., 2024, 12, 2766 DOI: 10.1039/D4BM00214H

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. You can use material from this article in other publications, without requesting further permission from the RSC, provided that the correct acknowledgement is given and it is not used for commercial purposes.

To request permission to reproduce material from this article in a commercial publication, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party commercial publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements