Synthetic strategies for fluorination of carbohydrates

María Laura Uhrig; Beatriz Lantaño; Al Postigo

doi:10.1039/C9OB00405J

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Synthetic strategies for fluorination of carbohydrates

María Laura Uhrig,

^ab Beatriz Lantaño^c and Al Postigo

*^c

Author affiliations

* Corresponding authors

^a Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Química Orgánica, Pabellón 2, Ciudad Universitaria, C1428EG Buenos Aires, Argentina

^b Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)-UBA. Centro de Investigación en Hidratos de Carbono (CIHIDECAR), Buenos Aires, Argentina

^c Departmento de Química Orgánica, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junin 954 CP1113-Buenos Aires, Argentina
E-mail: apostigo@ffyb.uba.ar

Abstract

This review article discusses different synthetic strategies for accomplishing regio- and stereoselective fluorinations of the sugar moiety, discussing the reaction mechanisms and some biological implications arising from such substitutions.

This article is part of the themed collections: Chemical Biology in OBC, Celebrating Latin American Talent in Chemistry and Synthetic methodology in OBC

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Article information

DOI: https://doi.org/10.1039/C9OB00405J
Article type: Review Article
Submitted: 18 feb. 2019
Accepted: 12 apr. 2019
First published: 12 apr. 2019

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Org. Biomol. Chem., 2019,17, 5173-5189

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Synthetic strategies for fluorination of carbohydrates

M. L. Uhrig, B. Lantaño and A. Postigo, Org. Biomol. Chem., 2019, 17, 5173 DOI: 10.1039/C9OB00405J

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Organic & Biomolecular Chemistry

Synthetic strategies for fluorination of carbohydrates

Abstract

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Synthetic strategies for fluorination of carbohydrates

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