Themed collection 2022 Reviews in RSC Advances

In studying secondary structural propensities of proteins by nuclear magnetic resonance (NMR) spectroscopy, secondary chemical shifts (SCSs) are the primary atomic scale observables. But which random coil chemical shift (RCCS) values to choose?

For biomedical applications, various delivery methods have been studied, including penetrating peptides, stimuli-sensitive chemistry, endosomal escape, and fusogenic liposome for enhancing the cytosolic delivery efficiency of biomolecules.

This review endeavors to delineate critical issues pertaining to the application of MXene-based composites against antibiotic-resistant bacteria.

Safranine and luminol having a unique polymeric constructor combined with different nanomaterials were explored as sensors for different analytes through electrochemical and chemical techniques.

Research progress of catalysts of the aldol condensation reaction of biomass based compounds is summarized for the synthesis of liquid fuel precursors and chemicals.

KuQuinones: from serendipity synthesis to photo(electro)chemical and biomedical applications.

Contamination, mobility, sources, and exposure of arsenic (one of the regulated elements) in the environment are investigated and discussed comprehensively.

4-Quinolone and its analogs are heterocyclic classes of organic compounds displaying biologically active and a broad spectrum of pharmaceutical drug scaffolds.

Approaches to overcome the challenges of cancer nanomedicine drug discovery process.

The performance of magnesium alloy implants has been continuously improved in recent years. This review discusses the types, corrosion mechanisms and corrosion control of medical magnesium alloys in recent years.

Conductive hydrogels are recognized as promising materials for wound healing. Valuable properties of conductive hydrogels suggest the possibility of their use as an alternative wound dressing to traditional dressings such as bandages.

Benzyne is a relatively active intermediate, which can be used to construct diverse compounds with complex structures and potential applications via the cyclization reaction of benzyne generated in situ from various precursors.

Covalent organic frameworks (COFs) are crystal-like organic structures such as cartography buildings prepared from appropriately pre-designed construction block precursors and are deployed for wound healing purposes.

This review article provides an intensive state-of-the-art over the period 2000–2022 centred around the discovery, classifications, biosynthetic pathways and therapeutic potentialities of 351 structurally diverse fungal containing-isocoumarins.

Microorganisms evolve resistance to antibiotics as a function of evolution. Antibiotics have accelerated bacterial resistance through mutations and acquired resistance through a combination of factors.

The formulation of poorly soluble drugs is an intractable challenge in the field of drug design, development and delivery.

Various approaches to control the release of active molecules or drug molecules through electrospun polymeric nanofibers.

Design points and applicable scenarios for bioinks in in situ 3D bioprinting.

Recent updates on the synthesis of CF₃-containing spirocyclic-oxindoles by employing N-2,2,2-trifluoroethylisatin ketimines are described in this review article.

An overview of applications of nanoparticles and their combinations with a variety of antiviral drugs.

Organic pollutants in water pose serious risks to both human health and ecological systems; thus, semiconductor/graphene nanocomposites are used as effective photocatalysts for their removal.

The enzymatic modification of protein serine or threonine residues by N-acetylglucosamine, namely O-GlcNAcylation, is a ubiquitous post-translational modification that frequently occurs in the nucleus and cytoplasm.

In the field of targeted drug delivery, the effects of size and morphology of drug nanocarriers are of great importance and need to be discussed in depth.

DTT: a potential electron rich building block and its diverse application in organic electronic materials.

The hydrogen storage properties, regulation methods and applications of Ti–Mn hydrogen storage alloys were reviewed.

A bio-responsive nanoparticle was formed by the directed self-assembly (DSA) of a hydrophobic NIR-fluorophore with poloxamer P₁₈₈.

A review on the progress in experimental, simulation and theoretical studies for the modification of MnO₂-based electrode materials from different perspectives of morphology, defect and heterojunction engineering.

The optimization mechanism of ultrafast laser machining is introduced. The specific applications of laser processed 3D micro/nano structures in optical, electrochemical and biomedical fields are elaborated, and perspectives are presented.

Cannabinoid receptors belong to the large family of G-protein-coupled receptors, which can be divided into two receptor types, cannabinoid receptor type-1 (CB1) and cannabinoid receptor type-2 (CB2).

This review provides a comprehensive overview of multicomponent reactions (MCRs) for the synthesis of biologically active 2-pyridone-containing heterocycles.

Dendrimers are branched molecules with well-defined lengths, shapes, molecular weights, and monodispersity in comparison to linear polymers.

Corchorus olitorius L. is a nutritious green leafy vegetable that is eaten as a viscous soup in African and Middle Eastern cultures.

Harmful metal ions and toxic anions produced in industrial processes cause serious damage to the environment and human health.

This review summarized recent advances in micro-/nanostructure array (microrods, nanowires, and hierarchical microstructures) integrated microfluidic devices for high-throughput separation of circulating tumor cells for early cancer detection.

Water contamination has become a significant issue on a global scale.

Natural products provide chemical diversity of antivibrio compounds.

Recent progress to improve the sustainability and biodegradability of synthetic rubber by incorporating raw materials from biological sources.

RNAi based gene silencing is a novel and environmental sustainable technique to control pests in crops and plants. Cationic polymers act as an important transfection agent thus improving the stability and efficiency of the process.

Polyamide (PA) reverse osmosis and nanofiltration membranes have been applied widely for desalination and wastewater reuse in the last 5–10 years.

Recent challenges on the metal induced crystallization (MIC) of amorphous semiconductors (a-Si and a-Ge) for potential applications in high-density data storage devices, flat panel displays, and high performance solar cells.

Hypoxia is a distinctive feature of most solid tumors due to insufficient oxygen supply of the abnormal vasculature, which cannot work with the demands of the fast proliferation of cancer cells.

In this paper, the structure of three TiO₂ polymorphs are introduced, then the preparation and electrochemical properties of TiO₂ with different morphologies and the related research on the composite with carbon and other materials are discussed.

Nitrogen fixation by organometallic catalysts at room temperature and pressure as an alternative route of Haber–Bosch process.

This review highlights recent (2016–2022) annulations of 1-indanones for the construction of various fused- and spiro carbo- and heterocyclic frameworks.

Biomarker targeted therapy approaches for TNBC using metal oxide-based NPs are highly effective and promising.

Attachment of biomolecules to polyaniline.

This review gives a full-scale and in-depth summary of mixed halide CsPbX3 perovskite materials for the photovoltaic application.

Cu_xO nanostructured thin films are potentially appealing materials for many applications. The deposition technique, SILAR, explored in this paper offers many advantages.

This review briefly summarizes evidence that links toxic metals to onset and progression of Alzheimer's disease. It discusses the structure and fabrication of optical chemosensors, and their use for monitoring toxic metals in water.

The article covers the outstanding features of fiber-reinforced vitrimer composites, including their reprocessing, recycling and self-healing properties.

Self-healing is the ability of a material to recover from physical damage.

Common positions for the incorporation of the radioisotopes carbon-14, sulfur-35, or tritium in oligonucleotides with the example of the two nucleotides thymidine as pyrimidine base and adenosine as purine base.

Pure water is one of the major requirements for living beings but water bodies are contaminated with toxic pollutants and heavy metals.

Metal organic frameworks (MOFs) are attracting significant attention for applications including adsorption, chemical sensing, gas separation, photocatalysis, electrocatalysis and catalysis.

PET (polyethylene terephthalate) has good transparency, corrosion resistance, gas barrier properties and mechanical properties, and is widely used in beverage bottles, fabrics, food packaging, tires, films, engineering plastics and other fields.

Two-dimensional van der Waals heterostructures (vdWHs) with tunable band alignment have the potential to be benignant in the development of minimal multi-functional and controllable electronics, but they have received little attention thus far.

Fluorescence immunosensors constructed from functional nanomaterials for the detection of tumor biomarkers such as enzymes, RNA, DNA, proteins and cancer cells were summarized.

Hepatocellular carcinoma (HCC) is a common malignancy threatening human health, and existing diagnostic and therapeutic techniques are facing great challenges.

3,5-Diyliden-4-piperidone scaffold are considered as curcumin mimic exhibiting diverse bio-properties.

FDA-approved antiviral agents represent an important class that has attracted attention in recent years to combat current and future threats of viral pandemics.

VO₂ based energy saving smart coatings are of great interest in research and industry due to the reversible crystalline structural transition of VO₂ which can induce significant transmittance and reflectance changes in the infrared range.

Creatinine is an amino acid derived from creatine catabolism at different steps of the body's organs, and its detection is significant because levels out of normal values are linked to some diseases like kidney failure.

The electrochemical reaction of amines, nitriles, amides, nitroaromatics, and imines has been proven to be a valuable method for the synthesis of various nitrogen-containing organic compounds.

This review highlights recent heterocyclization of the nitroenediamine derivatives based on catalyst and catalyst-free approaches from 2012 onwards.

In this review, we have discussed recent developments on the direct selenosulfonylation of unsaturated compounds which lead to the formation of two new carbon-sulfur and carbon-selenium bonds in a single operation.

With the rapid development of DNA nanotechnology, the emergence of stimulus-responsive dynamic DNA nanostructures (DDNs) has great potential applications in the biomedical field.

The increasing CO₂ concentration in the atmosphere has caused profound environmental issues such as global warming.

Photoredox catalysis has been explored for chemical reactions by irradiation of photoactive catalysts with visible light, under mild and environmentally benign conditions.

A comprehensive overview of nickel sulfide and phosphide electrocatalysts in the HER.

Antibiotic resistance is one of the critical health issues, describing a significant social health complication globally.