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An electrochemical-TUNEL method was developed for a cell sensor. A 3-D bio-interface based on CNT@PDA–FA was employed in the cytosensor, which significantly improved the cell capture. By coupling with a QD-based nanoprobe and electrochemical stripping analysis, the cytosensor exhibited attractive performance for detection of apoptotic cells.

Graphical abstract: An electrochemical-TUNEL method for sensitive detection of apoptotic cells

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