A novel dual-functional fluorescent probe was developed enabling real-time tracking of intracellular NAD(P)H flux and mitochondrial functional decline at the single-cell level with high precision. This probe could assess mitochondrial damage and energy metabolism disruptions in PD-related dopaminergic toxicity models.
Q. Tang, B. Jiang, M. yang, J. Guan, Q. Wang, Y. Qin and L. Wu, Chem. Commun., 2025, Accepted Manuscript , DOI: 10.1039/D5CC03654B
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