A redox-responsive selenium-containing pillar[5]arene-based macrocyclic amphiphile: synthesis, controllable self-assembly in water, and application in controlled release

Abstract

The first selenium-containing pillar[5]arene-based macrocyclic amphiphile was synthesized. This amphiphile self-assembled in water to form vesicles with redox responsiveness. Furthermore, these pillar[5]arene-based vesicles were used in the controlled release of small molecules with DOX as the model compound.