Issue 1, 2021

Biosynthesis of alkyne-containing natural products

Abstract

Alkyne-containing natural products are important molecules that are widely distributed in microbes and plants. Inspired by the advantages of acetylenic products used in the fields of medicinal chemistry, organic synthesis and material science, great efforts have focused on discovering the biosynthetic enzymes and pathways for alkyne formation. Here, we summarize the biosyntheses of alkyne-containing natural products and introduce de novo biosynthetic strategies for alkyne-tagged compound production.

Graphical abstract: Biosynthesis of alkyne-containing natural products

Article information

Article type
Review Article
Submitted
21 10 2020
Accepted
30 11 2020
First published
21 12 2020
This article is Open Access
Creative Commons BY-NC license

RSC Chem. Biol., 2021,2, 166-180

Biosynthesis of alkyne-containing natural products

X. Li, J. Lv, D. Hu and I. Abe, RSC Chem. Biol., 2021, 2, 166 DOI: 10.1039/D0CB00190B

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