Transformable nanoparticles to bypass biological barriers in cancer treatment

Mythili Ramachandran; Zhao Ma; Kai Lin; Cristabelle De Souza; Yuanpei Li

doi:10.1039/D2NA00485B

Transformable nanoparticles to bypass biological barriers in cancer treatment

Mythili Ramachandran,

^a Zhao Ma,^b Kai Lin,^c Cristabelle De Souza^d and Yuanpei Li

*^a

Author affiliations

* Corresponding authors

^a Department of Biochemistry and Molecular Medicine, University of California-Davis, USA
E-mail: lypli@ucdavis.edu

^b Department of Medicinal Chemistry, Key Laboratory of Chemical Biology, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China

^c College of Food Science and Engineering, Ocean University of China, Qingdao, China

^d Department of Pathology and Stem Cell Research, Stanford University, USA

Abstract

Nanomedicine based drug delivery platforms provide an interesting avenue to explore for the future of cancer treatment. Here we discuss the barriers for drug delivery in cancer therapeutics and how nanomaterials have been designed to bypass these blockades through stimuli responsive transformation in the most recent update. Nanomaterials that address the challenges of each step provide a promising solution for new cancer therapeutics.

This article is part of the themed collection: Recent Review Articles

Article information

https://doi.org/10.1039/D2NA00485B

Article type

Minireview

Submitted

27 7 2022

Accepted

03 9 2022

First published

14 9 2022

This article is Open Access

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Nanoscale Adv., 2022,4, 4470-4480

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Transformable nanoparticles to bypass biological barriers in cancer treatment

M. Ramachandran, Z. Ma, K. Lin, C. De Souza and Y. Li, Nanoscale Adv., 2022, 4, 4470 DOI: 10.1039/D2NA00485B

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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Transformable nanoparticles to bypass biological barriers in cancer treatment

Abstract

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Transformable nanoparticles to bypass biological barriers in cancer treatment

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