Issue 20, 2016
From the journal:

Journal of Materials Chemistry B

Low molecular weight gels induced differentiation of mesenchymal stem cells†

Yalong Hu,a   Wenxia Gao,*a   Fang Wu,b   Huayue Wu,a   Bin Heb  and  Jing He*b  

* Corresponding authors

a College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325027, China
E-mail: wenxiag@wzu.edu.cn

b National Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China
E-mail: jinghe30@scu.edu.cn

Abstract

Four low molecular weight gels (LMWGs) with different moduli were fabricated as scaffolds to investigate the differentiation of mesenchymal stem cells (MSCs). The MSCs differentiated to osteoblasts in rigid LMWGs and to chondrocytes in soft LMWGs. The critical modulus to induce the different differentiations was between 10 and 20 kPa.

Graphical abstract: Low molecular weight gels induced differentiation of mesenchymal stem cells

  • This article is part of the themed collection: Stem Cells
About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C5TB02546J
Article type
Communication
Submitted
03 Dec. 2015
Accepted
15 Febr. 2016
First published
16 Febr. 2016

J. Mater. Chem. B, 2016,4, 3504-3508

Author version available

Download author version (PDF)

Permissions

Request permissions

Low molecular weight gels induced differentiation of mesenchymal stem cells

Y. Hu, W. Gao, F. Wu, H. Wu, B. He and J. He, J. Mater. Chem. B, 2016, 4, 3504 DOI: 10.1039/C5TB02546J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements