Issue 3, 2017
From the journal:

Chemical Communications

An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells†

Nahyun Kwon,‡a   Myoung Ki Cho,‡b   Sang Jun Park,b   Dayoung Kim,a   Sang-Jip Nam,a   Lei Cui,*ac   Hwan Myung Kim ORCID logo *b  and  Juyoung Yoon ORCID logo *a  

* Corresponding authors

a Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Korea
E-mail: jyoon@ewha.ac.kr
Fax: +82-2-3277-2385
Tel: +82-2-3277-2400

b Department of Energy Systems Research, Ajou University, Suwon 443-749, Korea
E-mail: kimhm@ajou.ac.kr

c College of Science, University of Shanghai for Science and Technology, Shanghai, China
E-mail: cuilei15@usst.edu.cn

Abstract

A new quinone propionic acid locked TP fluorophore which can be used for human NAD(P)H:quinone oxidoreductase (hNQO1) detection was developed. The probe, TPQ, which displays high selectivity and anti-interference ability, was successfully applied to endogenous hNQO1 imaging and for the identification of different cancer cells.

Graphical abstract: An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells

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Article information

DOI
https://doi.org/10.1039/C6CC08971B
Article type
Communication
Submitted
10 Nov. 2016
Accepted
05 Dec. 2016
First published
05 Dec. 2016

Chem. Commun., 2017,53, 525-528

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An efficient two-photon fluorescent probe for human NAD(P)H:quinone oxidoreductase (hNQO1) detection and imaging in tumor cells

N. Kwon, M. K. Cho, S. J. Park, D. Kim, S. Nam, L. Cui, H. M. Kim and J. Yoon, Chem. Commun., 2017, 53, 525 DOI: 10.1039/C6CC08971B

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