Cultured cell-derived decellularized matrices: a review towards the next decade

Abstract

In the past decade, many cell-derived decellularized matrices have been prepared for various purposes. Cell-derived decellularized matrices have many advantages for inducing specific cell functions although there are still many problems that need to be solved. This review summarizes the points that need to be considered for the preparation of cell-derived decellularized matrices and provides examples of these matrices inducing cellular functions. Moreover, the problems that need to be solved in the next decade for the further application of cell-derived decellularized matrix technology have been summarized.