Cucurbit[8]uril-based supramolecular nanocapsules with a multienzyme-cascade antioxidative effect

Shengda Liu; Ruizhen Tian; Jiayun Xu; Liang Wang; Jianxin Sun; Xiaojia Jiang; Tingting Wang; Xiumei Li; Quan Luo; Junqiu Liu

doi:10.1039/C9CC07085K

Cucurbit[8]uril-based supramolecular nanocapsules with a multienzyme-cascade antioxidative effect†

Shengda Liu,‡^a Ruizhen Tian,‡^a Jiayun Xu,^a Liang Wang,^a Jianxin Sun,^a Xiaojia Jiang,^a Tingting Wang,^a Xiumei Li,^a Quan Luo

^a and Junqiu Liu

*^a

Author affiliations

* Corresponding authors

^a State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China
E-mail: junqiuliu@jlu.edu.cn

Abstract

A supramolecular nanocapsule was constructed by the ternary host–guest complexation of azobenzene (Azo) and methylviologen (MV) to cucurbit[8]uril (CB[8]) and the subsequent self-assembly. The supramolecular nanocapsule with both glutathione peroxidase (GPx) and superoxide dismutase (SOD) activities can mimic the intracellular enzymatic reactive oxygen species (ROS) defense system.

This article is part of the themed collection: Cucurbiturils and related cavitands

Chemical Communications

Cucurbit[8]uril-based supramolecular nanocapsules with a multienzyme-cascade antioxidative effect†

Abstract

Supplementary files

Article information

Download Citation

Permissions

Cucurbit[8]uril-based supramolecular nanocapsules with a multienzyme-cascade antioxidative effect

Social activity

Search articles by author

Spotlight

Advertisements