Issue 2, 2019
From the journal:

Natural Product Reports

The 6π-azaelectrocyclization of azatrienes. Synthetic applications in natural products, bioactive heterocycles, and related fields

Didier F. Vargas, ORCID logo a   Enrique L. Larghi ORCID logo a  and  Teodoro S. Kaufman ORCID logo *a  

* Corresponding authors

a Instituto de Química Rosario (IQUIR, CONICET-UNR), Facultad de Ciencias Bioquímicas y Farmacéuticas – Universidad Nacional de Rosario, Suipacha 531, 2000 Rosario, Argentina
E-mail: kaufman@iquir-conicet.gov.ar

Abstract

Covering: 2006 to 2018

The application of the 6π-azaelectrocyclization of azatrienes as a key strategy for the synthesis of natural products, their analogs and related bioactive or biomedically-relevant compounds (from 2006 to date) is comprehensively reviewed. Details about reaction optimization studies, relevant reaction mechanisms and conditions are also discussed.

Graphical abstract: The 6π-azaelectrocyclization of azatrienes. Synthetic applications in natural products, bioactive heterocycles, and related fields

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Article information

DOI
https://doi.org/10.1039/C8NP00014J
Article type
Review Article
Submitted
08 Febr. 2018
First published
09 Aug. 2018

Nat. Prod. Rep., 2019,36, 354-401

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The 6π-azaelectrocyclization of azatrienes. Synthetic applications in natural products, bioactive heterocycles, and related fields

D. F. Vargas, E. L. Larghi and T. S. Kaufman, Nat. Prod. Rep., 2019, 36, 354 DOI: 10.1039/C8NP00014J

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