Issue 35, 2023
From the journal:

Chemical Communications

Palladium-catalyzed intramolecular oxypalladation-initiated cascade: solvent-dependent chemodivergent approach to functionalized benzazepines and tetrahydroquinolines†

Anish Gupta, ORCID logo a   Tanvi Jandial,a   Muthu Karuppasamy,a   Nattamai Bhuvanesh,b   Subbiah Nagarajan, ORCID logo c   C. Uma Maheswari ORCID logo d  and  Vellaisamy Sridharan ORCID logo *a  

* Corresponding authors

a Department of Chemistry and Chemical Sciences, Central University of Jammu, Rahya-Suchani (Bagla), District-Samba, Jammu, JK, India
E-mail: vesridharan@gmail.com, sridharan.che@cujammu.ac.in

b Department of Chemistry, Texas A & M University, College Station, Texas, USA

c Department of Chemistry, National Institute of Technology, Warangal, Warangal, Telangana, India

d Department of Chemistry, School of Chemical and Biotechnology, SASTRA Deemed University, Thanjavur, Tamil Nadu, India

Abstract

Palladium-catalyzed, solvent-dependent intramolecular oxypalladation-triggered domino sequences of internal alkynes bearing tethered nucleophilic carboxylic ester and electrophilic enone functionalities were developed for the chemodivergent synthesis of two completely distinct biologically significant complex molecules including isochromenone-fused benzazepines and isobenzofuranone-fused tetrahydroquinolines/chromanes in a single synthetic operation.

Graphical abstract: Palladium-catalyzed intramolecular oxypalladation-initiated cascade: solvent-dependent chemodivergent approach to functionalized benzazepines and tetrahydroquinolines

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/D3CC01370G
Article type
Communication
Submitted
20 Marts 2023
Accepted
30 Marts 2023
First published
30 Marts 2023

Chem. Commun., 2023,59, 5233-5236

Permissions

Request permissions

Palladium-catalyzed intramolecular oxypalladation-initiated cascade: solvent-dependent chemodivergent approach to functionalized benzazepines and tetrahydroquinolines

A. Gupta, T. Jandial, M. Karuppasamy, N. Bhuvanesh, S. Nagarajan, C. U. Maheswari and V. Sridharan, Chem. Commun., 2023, 59, 5233 DOI: 10.1039/D3CC01370G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements