Issue 25, 2015
From the journal:

Chemical Communications

DNA-aptamer gating membranes†

Thomas Schäfer*ab  and  Veli Cengiz Özalpc  

* Corresponding authors

a POLYMAT, University of the Basque Country, Av. Tolosa 72, 20018 Donostia-San Sebastián, Spain
E-mail: thomas.schafer@ehu.es
Fax: +34 943 01 7065
Tel: +34 943 01 8266/8399

b Ikerbasque, Basque Foundation for Science, Bilbao, Spain

c School of Medicine, Istanbul Kemerburgaz University, 34217 Istanbul, Turkey

Abstract

This report describes a membrane barrier whose permeability is modulated through the recognition of a small-molecule target, adenosine triphosphate (ATP), by a DNA-aptamer. The gating function of the DNA-aptamer in the stimulus-responsive membrane was shown to be specific, concentration dependent, and reversible.

Graphical abstract: DNA-aptamer gating membranes

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Article information

DOI
https://doi.org/10.1039/C4CC09660F
Article type
Communication
Submitted
03 Dec. 2014
Accepted
14 Janv. 2015
First published
15 Janv. 2015
This article is Open Access
Creative Commons BY license

Chem. Commun., 2015,51, 5471-5474

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DNA-aptamer gating membranes

T. Schäfer and V. C. Özalp, Chem. Commun., 2015, 51, 5471 DOI: 10.1039/C4CC09660F

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