SERS-active silver nanoparticle trimers for sub-attomolar detection of alpha fetoprotein

Xiaoling Wu; Pan Fu; Wei Ma; Liguang Xu; Hua Kuang; Chuanlai Xu

doi:10.1039/C5RA12629K

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

SERS-active silver nanoparticle trimers for sub-attomolar detection of alpha fetoprotein†

Xiaoling Wu,^a Pan Fu,^a Wei Ma,^a Liguang Xu,^a Hua Kuang^a and Chuanlai Xu*^a

Author affiliations

* Corresponding authors

^a State Key Lab of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, People's Republic of China
E-mail: xcl@jiangnan.edu.cn

Abstract

SERS-active silver nanoparticle trimers were assembled in this study for the first time, through the aptamer of a cancer biomarker, alpha fetoprotein (AFP). It was successfully used for the sub-attomolar detection of AFP, with a limit of detection as low as 0.097 aM, which is the lowest reported so far.

This article is part of the themed collection: Surface enhanced Raman Spectroscopy: Editors collection for RSC Advances

Download options Please wait...

Supplementary files

Supplementary information PDF (503K)

Article information

DOI: https://doi.org/10.1039/C5RA12629K
Article type: Communication
Submitted: 30 Jūn. 2015
Accepted: 21 Aug. 2015
First published: 24 Aug. 2015

Download Citation

RSC Adv., 2015,5, 73395-73398

Permissions

Request permissions

SERS-active silver nanoparticle trimers for sub-attomolar detection of alpha fetoprotein

X. Wu, P. Fu, W. Ma, L. Xu, H. Kuang and C. Xu, RSC Adv., 2015, 5, 73395 DOI: 10.1039/C5RA12629K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

RSC Advances

SERS-active silver nanoparticle trimers for sub-attomolar detection of alpha fetoprotein†

Abstract

Supplementary files

Article information

Download Citation

Permissions

SERS-active silver nanoparticle trimers for sub-attomolar detection of alpha fetoprotein

Social activity

Search articles by author

Spotlight

Advertisements