Analyte-directed formation of emissive excimers for the selective detection of polyamines

Abstract

A convenient and selective method for the sensing of polyamines, which are important biomarkers for cancers, has been developed. The fluorescence light-up mechanism utilizes the analyte-induced formation of emissive excimers of a sulfonated probe. Detection is achieved in aqueous media and artificial urine samples, as indicated by an excellent fluorescence turn-on signal with a large spectral shift.