Issue 6, 2016
From the journal:

Molecular BioSystems

Understanding the chemically-reactive proteome

Lyn H. Jonesa  

a Worldwide Medicinal Chemistry, Pfizer, 610 Main Street, Cambridge MA, USA
E-mail: lyn.jones@pfizer.com

Abstract

The reactivity of amino acid residues in proteins is context-dependent and difficult to predict. Chemical biology can be used to understand the chemical modifications of proteins to help elucidate the nature of the reactive proteome. The resulting insights can be applied to pharmacoproteomics, target identification and molecular pathology.

Graphical abstract: Understanding the chemically-reactive proteome

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Article information

DOI
https://doi.org/10.1039/C5MB00760G
Article type
Opinion
Submitted
07 Nov. 2015
Accepted
22 Dec. 2015
First published
22 Dec. 2015

Mol. BioSyst., 2016,12, 1728-1730

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Understanding the chemically-reactive proteome

L. H. Jones, Mol. BioSyst., 2016, 12, 1728 DOI: 10.1039/C5MB00760G

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