Trifluoromethylthiolative 1,2-difunctionalization of alkenes with diselenides and AgSCF3

Abstract

An efficient regioselective difunctionalization of alkenes via trifluoromethylthiolation has been accomplished employing diaryl diselenide and AgSCF₃ in the presence of BF₃·OEt₂. Various substituted 1,2-dichalcogenated products having the SCF₃ moiety were synthesized in good to excellent yields under mild conditions. The preliminary mechanistic investigation revealed the possible reaction pathway and unique combination of diselenide and AgSCF₃ for successful transformation.