A dual-targeted CeO2–DNA nanosensor for real-time imaging of H2O2 to assess atherosclerotic plaque vulnerability

Zhenhua Liu; Yujie Cao; Xiaona Zhang; Huazhen Yang; Yujie Zhao; Wen Gao; Bo Tang

doi:10.1039/C9TB02459J

You do not have JavaScript enabled. Please enable JavaScript to access the full features of the site or access our non-JavaScript page.

A dual-targeted CeO₂–DNA nanosensor for real-time imaging of H₂O₂ to assess atherosclerotic plaque vulnerability†

Zhenhua Liu,‡^a Yujie Cao,‡^a Xiaona Zhang,^a Huazhen Yang,^a Yujie Zhao,^a Wen Gao*^a and Bo Tang

*^a

Author affiliations

* Corresponding authors

^a College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of Fine Chemicals, Shandong Normal University, Jinan, P. R. China
E-mail: gaowen@sdnu.edu.cn, tangb@sdnu.edu.cn

Abstract

A novel dual-targeted CeO₂–DNA nanosensor by modifying with folic acid (FA) and CD36 antibody was designed. This fluorescent nanosensor enables noninvasive imaging of alterations in H₂O₂in vitro and in vivo with good sensitivity and selectivity, accurately evaluating the inflammation level and providing early warning of plaque vulnerability.

This article is part of the themed collection: Biosensors

Download options Please wait...

Supplementary files

Supplementary information PDF (1332K)

Article information

DOI: https://doi.org/10.1039/C9TB02459J
Article type: Communication
Submitted: 03 Nov. 2019
Accepted: 09 Dec. 2019
First published: 10 Dec. 2019

Download Citation

J. Mater. Chem. B, 2020,8, 3502-3505

Permissions

Request permissions

A dual-targeted CeO₂–DNA nanosensor for real-time imaging of H₂O₂ to assess atherosclerotic plaque vulnerability

Z. Liu, Y. Cao, X. Zhang, H. Yang, Y. Zhao, W. Gao and B. Tang, J. Mater. Chem. B, 2020, 8, 3502 DOI: 10.1039/C9TB02459J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Social activity

Fetching data from CrossRef.
This may take some time to load.

Journal of Materials Chemistry B