Issue 1, 2021
From the journal:

Organic & Biomolecular Chemistry

Recent highlights of biosynthetic studies on marine natural products†

Jamshid Amiri Moghaddam, ORCID logo *a   Theresa Jautzus, ORCID logo a   Mohammad Alanjaryb  and  Christine Beemelmanns ORCID logo *a  

* Corresponding authors

a Junior Research Group Chemical Biology of Microbe-Host Interactions, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Beutenbergstr. 11a, 07745 Jena, Germany
E-mail: christine.beemelmanns@hki-jena.de

b Bioinformatics Group, Wageningen University, Wageningen, The Netherlands

Abstract

Marine bacteria are excellent yet often underexplored sources of structurally unique bioactive natural products. In this review we cover the diversity of marine bacterial biomolecules and highlight recent studies on structurally novel natural products. We include different compound classes and discuss the latest progress related to their biosynthetic pathway analysis and engineering: examples range from fatty acids over terpenes to PKS, NRPS and hybrid PKS–NRPS biomolecules.

Graphical abstract: Recent highlights of biosynthetic studies on marine natural products

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Article information

DOI
https://doi.org/10.1039/D0OB01677B
Article type
Review Article
Submitted
13 Aug. 2020
Accepted
29 Sept. 2020
First published
20 Nov. 2020
This article is Open Access
Creative Commons BY-NC license

Org. Biomol. Chem., 2021,19, 123-140

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Recent highlights of biosynthetic studies on marine natural products

J. Amiri Moghaddam, T. Jautzus, M. Alanjary and C. Beemelmanns, Org. Biomol. Chem., 2021, 19, 123 DOI: 10.1039/D0OB01677B

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