Recent advances in annulation reactions based on zwitterionic π-allyl palladium and propargyl palladium complexes

Abstract

In the past few years, Pd-catalyzed annulation reactions through zwitterionic π-allyl palladium intermediates have been extensively investigated. Meanwhile, zwitterionic π-allyl palladium and propargyl palladium have also been successfully demonstrated to be a vital and versatile synthon for the construction of carbocyclic and heterocyclic compounds, which include both structural scaffolds used in the pharmaceutical industry and novel heterocyclic skeletons with potential biological appeal. This review highlights representative advances in organic synthesis based on zwitterionic π-allyl palladium and propargyl palladium.