An NO-responsive probe for detecting acute inflammation using NIR-II fluorescence/optoacoustic imaging

Zunpan She; Junjie Chen; Lihe Sun; Fang Zeng; Shuizhu Wu

doi:10.1039/D2CC05386A

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An NO-responsive probe for detecting acute inflammation using NIR-II fluorescence/optoacoustic imaging†

Zunpan She,^a Junjie Chen,^a Lihe Sun,^a Fang Zeng

*^a and Shuizhu Wu

*^a

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* Corresponding authors

^a State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, College of Materials Science and Engineering, South China University of Technology, Guangzhou 510640, China
E-mail: mcfzeng@scut.edu.cn, shzhwu@scut.edu.cn

Abstract

An NO-responsive probe for imaging acute inflammation was developed. The probe responds to in situ NO in acute inflammation sites such as LPS-induced acute dermatitis and MIA-induced acute joint inflammation with turn-on NIR-II fluorescence and optoacoustic signals.

This article is part of the themed collection: Chemosensors and Molecular Logic

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Article information

DOI: https://doi.org/10.1039/D2CC05386A
Article type: Communication
Submitted: 02 Okt. 2022
Accepted: 01 Nov. 2022
First published: 02 Nov. 2022

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Chem. Commun., 2022,58, 13123-13126

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An NO-responsive probe for detecting acute inflammation using NIR-II fluorescence/optoacoustic imaging

Z. She, J. Chen, L. Sun, F. Zeng and S. Wu, Chem. Commun., 2022, 58, 13123 DOI: 10.1039/D2CC05386A

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Chemical Communications

An NO-responsive probe for detecting acute inflammation using NIR-II fluorescence/optoacoustic imaging†

Abstract

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An NO-responsive probe for detecting acute inflammation using NIR-II fluorescence/optoacoustic imaging

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