Issue 47, 2022
From the journal:

Nanoscale

Incorporating zeolitic-imidazolate framework-8 nanoparticles into kidney scaffolds: a first step towards innovative renal therapies†

Fátima Guerrero,*ab   Victoria Pulido,ab   Said Hamad, ORCID logo e   Pedro Aljama,ab   Alejandro Martín-Maloabcd  and  Carolina Carrillo-Carrión ORCID logo *fg  

* Corresponding authors

a Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, 14004 Córdoba, Spain
E-mail: fatima.guerrero@imibic.org

b Department of Medicine, University of Cordoba, 14004 Córdoba, Spain

c Nephrology Unit, Reina Sofia University Hospital, 14004 Córdoba, Spain

d Spanish Renal Research Network, Institute of Health Carlos III, 28040 Madrid, Spain

e Department of Physical, Chemical and Natural Systems, University Pablo de Olavide, 41013 Seville, Spain

f Institute for Chemical Research (IIQ), CSIC-University of Seville, 41092 Sevilla, Spain
E-mail: carolina.carrillo@csic.es

g Department of Organic Chemistry, Faculty of Chemistry, University of Seville, 41012 Seville, Spain

Abstract

We demonstrate for the first time the potential of zeolitic-imidazolate framework-8 nanoparticles to be incorporated within a renal scaffold while retaining their ability to remove uremic toxins (mainly hydrophobic toxins like p-cresol) under flow conditions. This work may pave the way for the future development of novel adsorbents for dialysis and/or artificial kidneys.

Graphical abstract: Incorporating zeolitic-imidazolate framework-8 nanoparticles into kidney scaffolds: a first step towards innovative renal therapies

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Article information

DOI
https://doi.org/10.1039/D2NR04246K
Article type
Communication
Submitted
01 Aug. 2022
Accepted
01 Nov. 2022
First published
03 Nov. 2022
This article is Open Access
Creative Commons BY-NC license

Nanoscale, 2022,14, 17543-17549

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Incorporating zeolitic-imidazolate framework-8 nanoparticles into kidney scaffolds: a first step towards innovative renal therapies

F. Guerrero, V. Pulido, S. Hamad, P. Aljama, A. Martín-Malo and C. Carrillo-Carrión, Nanoscale, 2022, 14, 17543 DOI: 10.1039/D2NR04246K

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