Biosafety evaluation of dual-responsive neutrobots
Zhiguang
Wu 
*a
and
Qiang
He
ab
*a
and
Qiang
He
ab
Abstract
The toxicity effects of paclitaxel (PTX)-loaded magnetic neutrophil-hybrid swimming microrobots (“neutrobots”) in vivo were assessed after intravenous administration to mice. The mice after 72 hours exhibited minimal immunotoxicity and liver and kidney toxicity at an administration dose of 3 × 106 PTX-loaded neutrobots. The minor toxicity of drug-loaded neutrobots holds considerable promise for biomedical applications.
- This article is part of the themed collections: Journal of Materials Chemistry B Emerging Investigators and Journal of Materials Chemistry B HOT Papers
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