Synthesis of unsymmetrical ketones via dual catalysed cross-coupling of α,β-unsaturated carboxylic acids with aryldiazonium salts

Abstract

A visible light-enabled synthesis of unsymmetrical ketones has been accomplished by the cross-coupling of α,β-unsaturated carboxylic acids and aryldiazonium salts embracing a synergistic eosin Y and Co(OAc)₂·4H₂O catalysis. The reaction involves decarboxylative aerobic CC bond cleavage, and is endowed with the creation of new C–C and C–O bonds with good substrate scope.